SCHEMBL8812499

SCHEMBL8812499

COc1cc(OC)nc(C(=O)c2cccc(Cl)c2C(=O)O)n1.[NaH]

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8802402 0.87 NPSR1 (0.47) NPSR1
SCHEMBL8812485 0.86 NPSR1 (0.44) NPSR1
SCHEMBL8809732 0.85 NPSR1 (0.43) NPSR1
SCHEMBL8809985 0.83 KDM4E (0.49)
SCHEMBL2289383 0.82 NPSR1 (0.47) NPSR1
SCHEMBL997634 0.82 KDM4E (0.50)
SCHEMBL2283859 0.78 NPSR1 (0.44) NPSR1
SCHEMBL1720555 0.77 CYP1A2 (0.48) NPSR1
SCHEMBL28345038 0.77
Pyrithiobac SCHEMBL2114064 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461079-B1 Substituted phthalides and heterocyclic phthalides CIBA GEIGY AG (CH) 1997-07-16 EP disclosed
US-5627138-A HERBICIDES SANDOZ LTD. (CH) 1997-05-06 US disclosed
US-5627137-A HERBICIDES SANDOZ LTD. (CH) 1997-05-06 US disclosed
US-5561101-A HERBICIDES SANDOZ LTD. (CH) 1996-10-01 US disclosed
US-5506192-A HERBICIDES SANDOZ LTD. 1996-04-09 US disclosed
EP-0461079-A2 Substituted phthalides and heterocyclic phthalides SANDOZ LTD. (CH) 1991-12-11 EP disclosed