Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997634 | 0.98 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10 | |
| Isopropylamine SCHEMBL9565383 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8809973 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10 | |
| Isopropylamine SCHEMBL8953470 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8812499 | 0.83 | NPSR1 (0.44) | — | |
| SCHEMBL2284904 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL9570533 | 0.80 | CA12 (0.38) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2290901 | 0.78 | CHRM4 (0.36) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2288979 | 0.75 | CYP1A2 (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL10181023 | 0.75 | CYP1A2 (0.53) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461079-B1 | Substituted phthalides and heterocyclic phthalides | CIBA GEIGY AG (CH) | 1997-07-16 | — | — | EP | claimed |