Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815000 | 0.78 | KDM4E (0.48) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8815136 | 0.77 | KDM4E (0.47) | KMT2AMEN1POLBSMN1; SMN2MAPT | |
| SCHEMBL27918824 | 0.72 | CYP1A1 (0.49) | KMT2AMEN1CYP1A1CYP1B1PTGES | |
| SCHEMBL28805636 | 0.71 | PTGES (0.51) | KMT2AMEN1CYP1A1CYP1B1PTGES | |
| SCHEMBL27918823 | 0.71 | PTGES (0.50) | KMT2AMEN1CYP1A1CYP1B1PTGES | |
| SCHEMBL3131983 | 0.67 | MAPT (0.53) | KMT2AMEN1POLBSMN1; SMN2MAPT | |
| SCHEMBL13973473 | 0.66 | KMT2A (0.66) | KMT2AMEN1POLBSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8812749 | 0.65 | MEN1 (0.40) | KMT2AMEN1CTSDMAPTKDM4E | |
| SCHEMBL2690193 | 0.65 | KMT2A (0.53) | KMT2AMEN1POLBSMN1; SMN2MAPT | |
| SCHEMBL11804252 | 0.64 | ERN1 (0.57) | KMT2AMEN1MAPTALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |