Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sultopride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 known ✓ | P14416 | 9/20 | 0.93 |
| ▸ | DRD3 | P35462 | 4/20 | 0.93 |
| ▸ | CA2 | P00918 | 2/20 | 0.93 |
| ▸ | DRD1 | P21728 | 2/20 | 0.93 |
| ▸ | DRD4 | P21917 | 2/20 | 0.93 |
| ▸ | CA9 | Q16790 | 2/20 | 0.93 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.93 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.93 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.93 |
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | TSHR | P16473 | 2/20 | 0.93 |
| ▸ | CA12 | O43570 | 1/20 | 0.93 |
| ▸ | CA1 | P00915 | 1/20 | 0.93 |
| ▸ | CA3 | P07451 | 1/20 | 0.93 |
| ▸ | MAPT | P10636 | 1/20 | 0.93 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.93 |
| ▸ | CA6 | P23280 | 1/20 | 0.93 |
| ▸ | CA5A | P35218 | 1/20 | 0.93 |
| ▸ | CA7 | P43166 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulpiride SCHEMBL29576250 | 0.96 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 | |
| Sulpiride SCHEMBL29359128 | 0.96 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 | |
| Levosulpiride SCHEMBL70112 | 0.96 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 | |
| Sulpiride SCHEMBL15475031 | 0.96 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 | |
| Levosulpiride SCHEMBL29406121 | 0.96 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 | |
| Sulpiride SCHEMBL8421 | 0.96 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 | |
| Sulpiride SCHEMBL11451373 | 0.95 | DRD2 (0.98) | DRD2DRD3CA2DRD1DRD4 | |
| Sulpiride SCHEMBL3836151 | 0.95 | DRD2 (0.98) | DRD2DRD3CA2DRD1DRD4 | |
| Sulpiride SCHEMBL28690022 | 0.95 | DRD2 (0.98) | DRD2DRD3CA2DRD1DRD4 | |
| Sultopride SCHEMBL149197 | 0.95 | DRD2 (1.00) | DRD2DRD3CA2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997004749-A1 | METHOD FOR PREPARING DRY PHARMACEUTICAL FORMS, AND RESULTING PHARMACEUTICAL COMPOSITIONS | LABORATOIRES EFFIK (FR) | 1997-02-13 | — | — | WO | disclosed |