Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814337 | 1.00 | SPHK1 (0.39) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL8810626 | 0.98 | SPHK1 (0.37) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL8813199 | 0.93 | ALDH1A1 (0.33) | SPHK1SPHK2ALDH1A1HSD17B10 | |
| SCHEMBL8810518 | 0.87 | ALDH1A1 (0.36) | ALDH1A1HSD17B10 | |
| SCHEMBL31086433 | 0.87 | SPHK1 (0.44) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL10119365 | 0.87 | SPHK1 (0.44) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL2525588 | 0.86 | SPHK1 (0.39) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL2527671 | 0.86 | SPHK1 (0.39) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL11858528 | 0.84 | SPHK1 (0.42) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL710231 | 0.83 | SPHK1 (0.37) | SPHK1SPHK2USP2HTTLPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |