Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5891922 | 0.99 | MEN1 (0.43) | MEN1KMT2ACYP1A2FNTAFNTB | |
| SCHEMBL9182362 | 0.85 | EGFR (0.55) | FNTAFNTBALDH1A1 | |
| SCHEMBL5891478 | 0.85 | EGFR (0.55) | FNTAFNTBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8075381 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL8075037 | 0.83 | MEN1 (0.39) | MEN1KMT2ACYP1A2HSD17B10 | |
| SCHEMBL5891488 | 0.83 | SCN9A (0.43) | KMT2A | |
| Hydrochloric Acid SCHEMBL8074695 | 0.80 | — | — | |
| SCHEMBL8073871 | 0.78 | EGFR (0.43) | KMT2AFNTAFNTBALDH1A1 | |
| SCHEMBL9186835 | 0.78 | MEN1 (0.42) | MEN1KMT2ACYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL8065794 | 0.77 | MEN1 (0.41) | MEN1KMT2ACYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001275-A1 | COMBINATIONS OF INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-01-16 | — | — | WO | disclosed |