Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.62 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | STAT5A | P42229 | 1/20 | 0.40 |
| ▸ | STAT5B | P51692 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812189 | 0.92 | SRC (0.65) | SRCYES1STAT5ASTAT5BGRB2 | |
| SCHEMBL8812940 | 0.80 | SRC (0.66) | SRCSTAT5ASTAT5B | |
| SCHEMBL8420879 | 0.79 | SRC (0.68) | SRCSTAT5ASTAT5B | |
| SCHEMBL8810755 | 0.78 | SRC (0.63) | SRCSTAT5ASTAT5B | |
| SCHEMBL8417324 | 0.76 | SRC (1.00) | SRCYES1 | |
| SCHEMBL8421232 | 0.69 | SRC (1.00) | SRCYES1STAT5ASTAT5B | |
| SCHEMBL8815818 | 0.66 | SRC (0.76) | SRCYES1 | |
| SCHEMBL8815972 | 0.66 | SRC (0.79) | SRCYES1 | |
| SCHEMBL12635593 | 0.64 | PTPN11 (0.52) | — | |
| SCHEMBL12636157 | 0.63 | KDM4E (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012903-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR INHIBITING THE BINDING OF PROTEINS CONTAINING AN SH2 DOMAIN TO COGNATE PHOSPHORYLATED PROTEINS | WARNER-LAMBERT COMPANY (US) | 1997-04-10 | — | — | WO | claimed |