Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.68 |
| ▸ | STAT5A | P42229 | 2/20 | 0.50 |
| ▸ | STAT5B | P51692 | 2/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810755 | 0.90 | SRC (0.63) | SRCSTAT5ASTAT5BLMNAPARP1 | |
| SCHEMBL8812940 | 0.88 | SRC (0.66) | SRCSTAT5ASTAT5BLMNA | |
| SCHEMBL8812189 | 0.82 | SRC (0.65) | SRCSTAT5ASTAT5B | |
| SCHEMBL8417324 | 0.81 | SRC (1.00) | SRC | |
| SCHEMBL8813451 | 0.79 | SRC (0.62) | SRCSTAT5ASTAT5B | |
| SCHEMBL8421232 | 0.71 | SRC (1.00) | SRCSTAT5ASTAT5B | |
| SCHEMBL9416636 | 0.71 | SMPD1 (0.70) | LMNAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9416543 | 0.71 | SMPD1 (0.70) | LMNAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL551533 | 0.71 | PARP1 (0.57) | LMNAMAPTL3MBTL1PARP1SMN1; SMN2 | |
| SCHEMBL6809852 | 0.71 | FOLH1 (0.57) | SGMS2LMNAL3MBTL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922697-A | Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |