Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8813581 | 0.99 | CA2 (0.60) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8812149 | 0.94 | CA2 (0.65) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8809028 | 0.93 | CA2 (0.64) | CA2CA4CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL8809173 | 0.93 | CA2 (0.64) | CA2CA4CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL8812219 | 0.93 | CA2 (0.62) | CA2CA4CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL8878046 | 0.89 | CA2 (0.74) | CA2CA4CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL9265905 | 0.87 | CA2 (0.65) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8811474 | 0.87 | CA2 (0.62) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8705806 | 0.86 | CA2 (0.82) | CA2CA4CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL8876611 | 0.86 | CA2 (0.61) | CA2CA4CA1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002825-A1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1997-01-30 | — | — | WO | claimed |