Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690587 | 1.00 | PARP1 (0.61) | PARP1PIM1PIM2ALDH1A1LMNA | |
| SCHEMBL8685837 | 0.93 | PARP1 (0.62) | PARP1PIM1PIM2ALDH1A1MEN1 | |
| SCHEMBL8811177 | 0.93 | PARP1 (0.62) | PARP1PIM1PIM2ALDH1A1MEN1 | |
| SCHEMBL8811679 | 0.90 | PARP1 (0.76) | PARP1PIM1PIM2MEN1KMT2A | |
| SCHEMBL8687701 | 0.90 | PARP1 (0.76) | PARP1PIM1PIM2MEN1KMT2A | |
| SCHEMBL8811988 | 0.89 | PARP1 (0.60) | PARP1PIM1PIM2ALDH1A1LMNA | |
| SCHEMBL8686453 | 0.89 | PARP1 (0.60) | PARP1PIM1PIM2ALDH1A1LMNA | |
| SCHEMBL8809167 | 0.89 | PARP1 (0.62) | PARP1PIM1PIM2ALDH1A1LMNA | |
| SCHEMBL8685371 | 0.89 | PARP1 (0.62) | PARP1PIM1PIM2ALDH1A1LMNA | |
| SCHEMBL8685959 | 0.88 | PARP1 (0.66) | PARP1ALDH1A1MEN1KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |