Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814541 | 1.00 | CHEK1 (0.50) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818039 | 0.93 | CHEK1 (0.50) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8817997 | 0.86 | CHEK1 (0.47) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8817990 | 0.86 | CHEK1 (0.47) | CHEK1PIM1IDO1LTKLIMK1 | |
| Diethylamine SCHEMBL8818049 | 0.86 | CHEK1 (0.47) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8441133 | 0.84 | IDO1 (0.45) | IDO1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8818181 | 0.83 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818171 | 0.83 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8814720 | 0.82 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818120 | 0.82 | CHEK1 (0.45) | CHEK1PIM1IDO1LTKLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016194-A1 | NAPHTHYLAZO INHIBITION OF AMYLOIDOSIS | WARNER-LAMBERT COMPANY (US) | 1997-05-09 | — | — | WO | claimed |