Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441520 | 0.84 | IDO1 (0.42) | IDO1CA12CA3CA4CA6 | |
| SCHEMBL8814540 | 0.84 | CHEK1 (0.50) | IDO1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8814541 | 0.84 | CHEK1 (0.50) | IDO1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL13478430 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1RECQLMAPT | |
| SCHEMBL8441211 | 0.81 | IDO1 (0.54) | IDO1CA12CA3CA4CA6 | |
| SCHEMBL8441204 | 0.81 | IDO1 (0.54) | IDO1CA12CA3CA4CA6 | |
| SCHEMBL8439697 | 0.79 | IDO1 (0.49) | IDO1CA12CA3CA4CA6 | |
| SCHEMBL12378825 | 0.77 | IDO1 (0.42) | IDO1CA12CA3CA4CA6 | |
| SCHEMBL8441127 | 0.77 | MEN1 (0.41) | MEN1KMT2AALDH1A1RECQLMAPT | |
| SCHEMBL8275182 | 0.76 | IDO1 (0.46) | IDO1CA12CA3CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |