Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291103 | 0.92 | CYP1A2 (0.39) | LMNACYP1A2ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL12079699 | 0.81 | CYP1A2 (0.34) | CYP1A2ALDH1A1MGAMGAASI | |
| SCHEMBL19770548 | 0.79 | NAAA (0.39) | LMNACYP1A2ALDH1A1MGAMGAA | |
| SCHEMBL176416 | 0.79 | HTR2C (0.38) | EGLN1PHF8KDM2AKDM6BKDM5C | |
| SCHEMBL262913 | 0.77 | MGAM (0.55) | EGLN1PHF8KDM2AKDM6BKDM5C | |
| Succinic Acid Diethyl Ester SCHEMBL27966388 | 0.77 | MGAM (0.55) | EGLN1PHF8KDM2AKDM6BKDM5C | |
| SCHEMBL363334 | 0.77 | MGAM (0.55) | EGLN1PHF8KDM2AKDM6BKDM5C | |
| Succinic Acid Diethyl Ester SCHEMBL27830938 | 0.77 | MGAM (0.55) | EGLN1PHF8KDM2AKDM6BKDM5C | |
| SCHEMBL17968318 | 0.75 | TDP1 (0.60) | ALDH1A1MAPT | |
| SCHEMBL5014278 | 0.74 | MGAM (0.52) | EGLN1PHF8KDM2AKDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698309-A | OXIDE PARTICLES HAVE BEEEN SUBJECTED TO SURFACE MODIFICATION WITH SILYLATING AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |