Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | KAT7 | O95251 | 4/20 | 0.35 |
| ▸ | KAT6B | Q8WYB5 | 4/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815435 | 0.90 | HCRTR2 (0.39) | HCRTR2KAT7KAT6BKAT6APDE4A | |
| SCHEMBL8815421 | 0.90 | MEN1 (0.39) | HCRTR2KAT7KAT6BKAT6APDE4A | |
| SCHEMBL8818366 | 0.89 | PTGDR2 (0.37) | HCRTR2KAT7KAT6BKAT6AHTT | |
| SCHEMBL8817353 | 0.89 | KAT7 (0.36) | HCRTR2KAT7KAT6BKAT6APDE4A | |
| SCHEMBL8817079 | 0.80 | KLKB1 (0.37) | KAT7KAT6BKAT6ANPC1RAB9A | |
| SCHEMBL8490794 | 0.79 | AVPR2 (0.39) | HCRTR2NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8815680 | 0.79 | PDE4D (0.37) | ALDH1A1SMN1; SMN2HTTHSP90AA1KDM4E | |
| SCHEMBL8818564 | 0.78 | CYP19A1 (0.38) | HCRTR2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL8817211 | 0.77 | PDE4D (0.35) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL8486767 | 0.77 | NR1H4 (0.41) | HCRTR2NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |