Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | KAT7 | O95251 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815432 | 0.90 | HCRTR2 (0.36) | HCRTR2PDE4AKAT7KAT6AKAT6B | |
| SCHEMBL8818564 | 0.88 | CYP19A1 (0.38) | HCRTR2BRD4KDM4ENPC1RAB9A | |
| SCHEMBL8815421 | 0.87 | MEN1 (0.39) | HCRTR2PDE4AKAT7KAT6AKAT6B | |
| SCHEMBL8817353 | 0.87 | KAT7 (0.36) | HCRTR2BRD4PDE4AKAT7KAT6A | |
| SCHEMBL8818366 | 0.87 | PTGDR2 (0.37) | HCRTR2KAT7KAT6AKAT6BHTT | |
| SCHEMBL8817679 | 0.85 | HCRTR2 (0.34) | HCRTR2BRD4KDM4ETSHRDRD4 | |
| SCHEMBL6292089 | 0.84 | TSHR (0.38) | HCRTR2BRD4HPGDKDM4ENPC1 | |
| SCHEMBL8813500 | 0.83 | BRD4 (0.33) | HCRTR2BRD4HPGDKDM4EHTT | |
| SCHEMBL8890586 | 0.82 | ALDH1A1 (0.37) | HCRTR2KDM4ETSHRHTTNPSR1 | |
| SCHEMBL9116296 | 0.82 | TSHR (0.36) | HCRTR2BRD4KDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |