Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888897 | 1.00 | HCAR2 (0.59) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL11259256 | 1.00 | HCAR2 (0.59) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL5164772 | 1.00 | HCAR2 (0.59) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL11257102 | 1.00 | HCAR2 (0.59) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL2485450 | 0.96 | ATM (0.61) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL4740627 | 0.96 | ATM (0.61) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL6931235 | 0.96 | HCAR2 (0.59) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL3772230 | 0.94 | HCAR2 (0.58) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL131584 | 0.94 | ATM (0.63) | HCAR2ATMNAAATSHRHPGD | |
| SCHEMBL8896661 | 0.92 | HCAR2 (0.59) | HCAR2ATMNAAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686548-A | POLYSILOXANES CONTAINING ANCHORING CHAINS FOR BINDING WITH A SOLID SURFACE THROUGH CHEMISORPTION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5686549-A | FUNCTIONALIZED POLYSILOXANES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |