SCHEMBL5164772

SCHEMBL5164772

CCCCCC[CH]C(=O)OCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.59
ATM Q13315 1/20 0.55
NAAA Q02083 1/20 0.53
TSHR P16473 5/20 0.52
HPGD P15428 1/20 0.52
EPHX1 P07099 1/20 0.50
FAAH O00519 2/20 0.49
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1888897 1.00 HCAR2 (0.59) HCAR2ATMNAAATSHRHPGD
SCHEMBL11259256 1.00 HCAR2 (0.59) HCAR2ATMNAAATSHRHPGD
SCHEMBL8815436 1.00 HCAR2 (0.59) HCAR2ATMNAAATSHRHPGD
SCHEMBL11257102 1.00 HCAR2 (0.59) HCAR2ATMNAAATSHRHPGD
SCHEMBL2485450 0.96 ATM (0.61) HCAR2ATMNAAATSHRHPGD
SCHEMBL4740627 0.96 ATM (0.61) HCAR2ATMNAAATSHRHPGD
SCHEMBL6931235 0.96 HCAR2 (0.59) HCAR2ATMNAAATSHRHPGD
SCHEMBL3772230 0.94 HCAR2 (0.58) HCAR2ATMNAAATSHRHPGD
SCHEMBL131584 0.94 ATM (0.63) HCAR2ATMNAAATSHRHPGD
SCHEMBL8896661 0.92 HCAR2 (0.59) HCAR2ATMNAAATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546141-B Benzotriazole derivative compound 希普洛化成股份有限公司 2023-03-28 CN disclosed
US-10919868-B2 Benzotriazole derivative compound SHIPRO KASEI KAISHA, LTD. (JP) 2021-02-16 US disclosed
US-10781187-B2 Benzotriazole derivative compound SHIPRO KASEI KAISHI, LTD. (JP) 2020-09-22 US disclosed
US-20200290981-A1 BENZOTRIAZOLE DERIVATIVE COMPOUND SHIPRO KASEI KAISHA, LTD. (JP) 2020-09-17 US disclosed
US-20200157059-A1 BENZOTRIAZOLE DERIVATIVE COMPOUND SHIPRO KASEI KAISHA, LTD. (JP) 2020-05-21 US disclosed
CN-110546141-A Benzotriazole derivative compound SHIPRO KASEI KAISHA LTD 2019-12-06 CN disclosed
EP-1370614-B1 THE USE OF AROMATIC COMPOUNDS AS PHASE DIRECTORS AND PARTICLE SIZE REDUCERS FOR QUINACRIDONE PIGMENTS CIBA SC HOLDING AG (CH) 2007-04-11 EP disclosed
US-6706215-B1 2-(2'-HYDROXYPHENYL)-1,3-PYRIMIDINE DERIVATIVE CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-16 US disclosed
EP-1370614-A1 THE USE OF AROMATIC COMPOUNDS AS PHASE DIRECTORS AND PARTICLE SIZE REDUCERS FOR QUINACRIDONE PIGMENTS Ciba SC Holding AG (CH) 2003-12-17 EP disclosed
US-6626990-B2 Using aromatic- or heteraromatic-compounds having at least one hydroxyl or keto group bonded to the ring, with the oxidation of corresponding dihydroquinacridone salts CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-30 US disclosed
US-20020161232-A1 Use of aromatic compounds as phase directors and particle size reducers for quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2002-10-31 US disclosed
WO-2002077104-A1 THE USE OF AROMATIC COMPOUNDS AS PHASE DIRECTORS AND PARTICLE SIZE REDUCERS FOR QUINACRIDONE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-03 WO disclosed
US-6060543-A STABILIZE ORGANIC MATERIAL AGAINST DAMAGE BY LIGHT, OXYGEN AND/OR HEAT CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-09 US disclosed
US-5753729-A COATING COMPOSITION COMPRISING ORGANIC POLYMER BINDER, 2-(2*-HYDROXYPHENYL)PYRIMIDINE STABILIZER CIBA SPECIALTY CHEMICALS CORPORATION 1998-05-19 US disclosed
US-5686233-A PHOTOGRAPHIC FILM STABILIZER CIBA-GEIGY CORPORATION (US) 1997-11-11 US disclosed
US-5668200-A Stabilizer combination CIBA-GEIGY CORPORATION (US) 1997-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157059-A1 BENZOTRIAZOLE DERIVATIVE COMPOUND CCNT2, CCNT1, SULT1A1 HCAR2 1483/4885ATM 692/4885NAAA 1292/4885
US-20020161232-A1 Use of aromatic compounds as phase directors and particle size reducers for quinacridone pigments QDPR, POLR2H, POLR2E HCAR2 1437/4885ATM 3135/4885NAAA 4296/4885
US-20200290981-A1 BENZOTRIAZOLE DERIVATIVE COMPOUND CCNT2, CCNT1, SULT1A1 HCAR2 1554/4885ATM 703/4885NAAA 1399/4885
US-10781187-B2 Benzotriazole derivative compound CCNT2, CCNT1, SULT1A1 HCAR2 1403/4885ATM 696/4885NAAA 1204/4885
US-10919868-B2 Benzotriazole derivative compound CCNT2, CCNT1, SULT1A1 HCAR2 1554/4885ATM 703/4885NAAA 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.