Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473986 | 0.85 | AHR (0.68) | AHRPTPN1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31174010 | 0.82 | TTR (0.67) | AHRTTRHPGDCASP1CASP7 | |
| SCHEMBL5346099 | 0.82 | TTR (0.67) | AHRTTRHPGDCASP1CASP7 | |
| SCHEMBL19661827 | 0.78 | AHR (0.50) | AHRPTPN1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16477279 | 0.78 | MAPT (0.50) | AHRCSNK2A2CSNK2BCSNK2A1TTR | |
| SCHEMBL31217546 | 0.77 | AHR (0.44) | AHRPTPN1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31619649 | 0.77 | AHR (0.44) | AHRPTPN1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29952252 | 0.75 | PTPN1 (0.51) | AHRPTPN1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL16480062 | 0.75 | KDM4E (0.65) | CSNK2A2CSNK2BHPGDHSD17B10CA12 | |
| SCHEMBL11541084 | 0.74 | PTPN1 (0.58) | AHRPTPN1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | disclosed |