SCHEMBL5346099

SCHEMBL5346099

O=c1c2ccccc2oc2c(Cl)cc(Cl)cc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 5/20 0.67
▸ MAOA P21397 6/20 0.55
▸ KDM4E B2RXH2 2/20 0.55
▸ ALDH1A1 P00352 2/20 0.55
▸ GLA P06280 1/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ MAPT P10636 1/20 0.55
▸ HPGD P15428 1/20 0.55
▸ PGAM1 P18669 1/20 0.55
▸ CASP1 P29466 1/20 0.55
▸ CASP7 P55210 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ HSD17B10 Q99714 1/20 0.55
▸ AHR P35869 3/20 0.50
▸ CA1 P00915 1/20 0.48
▸ CA2 P00918 1/20 0.48
▸ PTGS2 P35354 1/20 0.47
▸ NPC1 O15118 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31174010 1.00 TTR (0.67) TTRMAOAKDM4EALDH1A1GLA
SCHEMBL20739897 0.86 AHR (0.62) TTRSMN1; SMN2AHR
SCHEMBL16477282 0.84 TTR (0.63) TTRMAOAKDM4EALDH1A1GLA
SCHEMBL8815638 0.82 AHR (0.57) TTRHPGDCASP1CASP7HSD17B10
SCHEMBL25635987 0.81 TTR (0.53) TTRMAOAKDM4EALDH1A1GLA
SCHEMBL31193433 0.81 MAOA (0.64) TTRMAOAKDM4EALDH1A1GLA
SCHEMBL6570481 0.81 MAOA (0.64) TTRMAOAKDM4EALDH1A1GLA
SCHEMBL472763 0.80 AHR (0.50) TTRSMN1; SMN2AHR
SCHEMBL16477279 0.80 MAPT (0.50) TTRKDM4EALDH1A1CYP3A4MAPT
SCHEMBL19661827 0.80 AHR (0.50) TTRMAOAAHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163241-A1 ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION, CURED PRODUCT, LAMINATE ,AND ARTICLE DIC CORPORATION (JP) 2025-05-22 — — US disclosed
WO-2023171023-A1 ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION, CURED PRODUCT, LAMINATE ,AND ARTICLE DIC株式会社 2023-09-14 — — WO disclosed
CN-115725227-A Active energy ray-curable composition, cured product, and film DIC株式会社 2023-03-03 — — CN disclosed
US-9163002-B2 Methodology for the synthesis of xanthones UNIVERSITY OF SOUTH CAROLINA (US) 2015-10-20 — — US disclosed
US-9163002-B2 Methodology for the synthesis of xanthones UNIVERSITY OF SOUTH CAROLINA (US) 2015-10-20 — — US disclosed
US-20140107354-A1 New Methodology for the Synthesis of Xanthones UNIVERSITY OF SOUTH CAROLINA 2014-04-17 — — US disclosed
US-20140107354-A1 New Methodology for the Synthesis of Xanthones UNIVERSITY OF SOUTH CAROLINA 2014-04-17 — — US disclosed
US-7182453-B2 Ink jet recording apparatus and ink jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-27 — — US disclosed
US-20040141040-A1 Ink jet recording apparatus and ink jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2004-07-22 — — US disclosed
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 — — EP disclosed
US-4816496-A HEAT AND LIGHT RESISTANT ADHESIVES AND FILMS KABUSHIKI KAISHA TOSHIBA (JP) 1989-03-28 — — US disclosed
EP-0282634-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1988-09-21 — — EP disclosed
EP-0135887-B1 PHOTOCURABLE COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1988-04-06 — — EP disclosed
EP-0123842-B1 PHOTO-CURABLE EPOXY RESIN TYPE COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-19 — — EP disclosed
EP-0195846-A2 Photo-curable epoxy resin type composition and curing process KABUSHIKI KAISHA TOSHIBA (JP) 1986-10-01 — — EP disclosed
US-4599155-A POLYORTHOESTERS;SHRINKAGE INHIBITION;NONCRACKING;COATINGS KABUSHIKI KAISHA TOSHIBA (JP) 1986-07-08 — — US disclosed
EP-0172330-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-02-26 — — EP disclosed
EP-0139234-A2 Resin composition KABUSHIKI KAISHA TOSHIBA (JP) 1985-05-02 — — EP disclosed
EP-0135887-A2 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1985-04-03 — — EP disclosed
EP-0123842-A1 Photo-curable epoxy resin type composition KABUSHIKI KAISHA TOSHIBA (JP) 1984-11-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107354-A1 New Methodology for the Synthesis of Xanthones XDH, TYR, NISCH TTR 3971/4885MAOA 68/4885KDM4E 1101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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