SCHEMBL8816422

SCHEMBL8816422

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nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
PGD P52209 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2C9 P11712 1/20 0.37
PDE4A P27815 1/20 0.37
TP53 P04637 1/20 0.32
TET2 Q6N021 1/20 0.30
CPT2 P23786 1/20 0.30
ACLY P53396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2932039 1.00 TSHR (0.39) TSHRPGDALDH1A1CYP2C9PDE4A
SCHEMBL11503366 1.00 TSHR (0.39) TSHRPGDALDH1A1CYP2C9PDE4A
SCHEMBL28496880 1.00 TSHR (0.39) TSHRPGDALDH1A1CYP2C9PDE4A
SCHEMBL32676547 0.79 TSHR (0.43) TSHRPGDALDH1A1CYP2C9PDE4A
SCHEMBL722150 0.76 TSHR (0.43) TSHRPGDCYP2C9PDE4ACPT2
SCHEMBL22833252 0.76 TSHR (0.43) TSHRPGDCYP2C9PDE4ACPT2
SCHEMBL5356598 0.76 TSHR (0.43) TSHRPGDCYP2C9PDE4ACPT2
SCHEMBL14892562 0.76 TSHR (0.43) TSHRPGDCYP2C9PDE4ACPT2
SCHEMBL10439669 0.74 ALDH1A1 (0.39) TSHRPGDALDH1A1TP53TET2
SCHEMBL10433224 0.74 TSHR (0.41) TSHRPGDALDH1A1CYP2C9TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997023289-A1 OXIDATION CATALYST SYSTEM COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1997-07-03 WO disclosed