Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Cysteine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.76 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | GSR | P00390 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL8817342 | 1.00 | PTGS1 (0.76) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL8817362 | 1.00 | PTGS1 (0.76) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL11127428 | 0.98 | PTGS1 (0.80) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL431234 | 0.98 | PTGS1 (0.80) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL11127430 | 0.98 | PTGS1 (0.80) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL431233 | 0.98 | PTGS1 (0.80) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL28996192 | 0.95 | PTGS1 (0.76) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL7728523 | 0.95 | PTGS1 (0.76) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL28607761 | 0.95 | PTGS1 (0.76) | PTGS1SLC7A11ENPEPPMP22GSR | |
| Cysteine SCHEMBL29009435 | 0.91 | PTGS1 (0.70) | PTGS1SLC7A11ENPEPPMP22GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021469-A1 | IN-SITU TREATMENT OF WASTE STACKS, SOILS, EARTH AND OTHER MATERIALS TO IMMOBILIZE METALS CONTAINED THEREIN | J.R. SIMPLOT COMPANY (US) | 1997-06-19 | — | — | WO | disclosed |