SCHEMBL8817428

SCHEMBL8817428

O=C(O)CCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
TSHR P16473 4/20 0.42
NFKB1 P19838 2/20 0.42
PMP22 Q01453 1/20 0.42
THRB P10828 1/20 0.40
SLC22A6 Q4U2R8 2/20 0.39
GPR84 Q9NQS5 4/20 0.37
FFAR1 O14842 2/20 0.37
FFAR4 Q5NUL3 2/20 0.37
AKR1B1 P15121 1/20 0.37
CYP2D6 P10635 1/20 0.37
FOLH1 Q04609 1/20 0.37
ALDH1A1 P00352 3/20 0.36
PPARG P37231 5/20 0.35
PPARD Q03181 5/20 0.35
PPARA Q07869 5/20 0.35
HDAC11 Q96DB2 4/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7884128 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL10000306 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL1194865 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL23788184 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL9449787 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL23788019 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL11791107 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL1608462 0.98 TSHR (0.46) LMNATSHRNFKB1PMP22THRB
SCHEMBL8817917 0.98 LMNA (0.46) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL5679801 0.96 TSHR (0.48) LMNATSHRNFKB1PMP22THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240352163-A1 Preparation Method for Polytrifluorostyrene CHANGSHU 3F ZHONGHAO NEW CHEMICAL MATERIALS CO., LTD. (CN) 2024-10-24 US claimed
US-20240352163-A1 Preparation Method for Polytrifluorostyrene CHANGSHU 3F ZHONGHAO NEW CHEMICAL MATERIALS CO., LTD. (CN) 2024-10-24 US disclosed
WO-1997024387-A1 FLUORINE CONTAINING POLY (BETA-HYDROXYORGANOATE) MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-10 WO disclosed