Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8819636 | 0.99 | ADRB2 (0.40) | ADRB2ADRB1LMNATDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8818891 | 0.88 | MEN1 (0.41) | ADRB2ADRB1GLAADRB3CYP2D6 | |
| SCHEMBL8818005 | 0.85 | ADRB2 (0.41) | ADRB2ADRB1LMNATDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8817960 | 0.84 | MAPT (0.35) | LMNATSHR | |
| Hydrochloric Acid SCHEMBL8815936 | 0.84 | ADRB2 (0.41) | ADRB2ADRB1CYP1A2TSHRADRB3 | |
| Hydrochloric Acid SCHEMBL8817535 | 0.79 | CHEK1 (0.36) | LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL8817982 | 0.78 | CHEK1 (0.33) | LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL8815907 | 0.78 | CHEK1 (0.37) | LMNAKDM4EBLMPMP22CYP2C19 | |
| Hydrochloric Acid SCHEMBL8817962 | 0.76 | CHEK1 (0.35) | LMNATDP1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL8815942 | 0.76 | CHEK1 (0.39) | LMNATDP1KDM4ECYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027183-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |