Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.45 |
| ▸ | CPB1 | P15086 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14464497 | 0.83 | HRH3 (0.59) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL20008117 | 0.81 | HRH3 (0.46) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL2626826 | 0.81 | ADRA2A (0.63) | CYP19A1 | |
| SCHEMBL8820677 | 0.79 | HRH3 (0.53) | HRH3CYP19A1HRH4CPB2CPB1 | |
| SCHEMBL20966632 | 0.79 | HRH3 (0.47) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL25866505 | 0.79 | HRH3 (0.47) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL14415990 | 0.79 | HRH3 (0.54) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL22692972 | 0.77 | HRH3 (0.56) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL10613000 | 0.77 | HRH3 (0.56) | HRH3HRH4CPB2CPB1 | |
| SCHEMBL10858595 | 0.74 | HRH3 (0.53) | HRH3HRH4CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047623-A1 | IMIDAZOLE DERIVATIVES AS PROTECTIVE AGENTS IN REPERFUSION INJURY AND SEVERE INFLAMMATORY RESPONSES | CYTOS PHARMACEUTICALS LLC (US) | 1997-12-18 | — | — | WO | disclosed |