Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7867963 | 0.90 | DRD2 (0.44) | DRD2SLC6A4DRD3HTR2ACHRM4 | |
| Oxalic Acid SCHEMBL7864905 | 0.88 | DRD2 (0.46) | DRD2SLC6A4RORCDRD3CHRM4 | |
| Phosphoric Acid SCHEMBL7866432 | 0.82 | DRD2 (0.44) | DRD2SLC6A4DRD3HTR2ACHRM4 | |
| Oxalic Acid SCHEMBL7870888 | 0.80 | DRD2 (0.46) | DRD2SLC6A4DRD3CHRM4FASN | |
| Phosphoric Acid SCHEMBL7865116 | 0.71 | DRD2 (0.48) | DRD2SLC6A4HTR2A | |
| Phosphoric Acid SCHEMBL7867446 | 0.71 | SLC6A4 (0.44) | DRD2SLC6A4CHRNA7 | |
| Phosphoric Acid SCHEMBL7867952 | 0.70 | DRD2 (0.45) | DRD2SLC6A4CHRNA7 | |
| Phosphoric Acid SCHEMBL7867945 | 0.69 | HTR1D (0.53) | DRD2 | |
| Phosphoric Acid SCHEMBL7866413 | 0.69 | DRD2 (0.42) | DRD2SLC6A4DRD3HTR2ACHRM4 | |
| Phosphoric Acid SCHEMBL7864985 | 0.69 | DRD2 (0.42) | DRD2SLC6A4DRD3HTR2ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |