Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.63 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170898 | 0.83 | DHODH (0.54) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL8818566 | 0.82 | PARP1 (0.60) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL31027957 | 0.81 | DHODH (0.59) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL1889612 | 0.81 | PARP1 (0.80) | PARP1DHODH | |
| SCHEMBL8818540 | 0.81 | PARP1 (0.62) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL1830191 | 0.80 | DHODH (0.51) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL7146754 | 0.80 | DHODH (0.62) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL505343 | 0.79 | DHODH (0.57) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL4457030 | 0.79 | DHODH (0.53) | PARP1MGAMGAASIMGAM2 | |
| SCHEMBL230979 | 0.79 | DHODH (0.53) | PARP1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |