Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.53 |
| ▸ | PARP1 | P09874 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | MGAM | O43451 | 4/20 | 0.51 |
| ▸ | SI | P14410 | 4/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230979 | 0.97 | DHODH (0.53) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL31027957 | 0.93 | DHODH (0.59) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL9346643 | 0.93 | GAA (0.54) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL7146754 | 0.91 | DHODH (0.62) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL1170898 | 0.91 | DHODH (0.54) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL8818524 | 0.89 | MGAM (0.68) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL8817536 | 0.89 | NR1I3 (0.58) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL8816555 | 0.89 | DHODH (0.51) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL8891044 | 0.89 | MGAM (0.68) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL8816885 | 0.87 | DHODH (0.50) | DHODHPARP1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125752-A1 | HETEROCYCLIC BRIDGED BIPHENYLS | BASF SE (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008119666-A1 | HETEROCYCLIC BRIDGED BIPHENYLS | BASF SE (CH) | 2008-10-09 | — | — | WO | disclosed |