Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 5/20 | 0.61 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CDA | P32320 | 1/20 | 0.45 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432297 | 1.00 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL432298 | 1.00 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL432296 | 1.00 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL22972654 | 0.94 | P2RY6 (0.55) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL31160212 | 0.93 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL16904894 | 0.93 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL31160188 | 0.93 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL18852530 | 0.92 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL565905 | 0.92 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL16805383 | 0.92 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040124-A1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| EP-0570514-A4 | METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM | GILEAD SCIENCES INC (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0570514-A1 | METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM | GILEAD SCIENCES, INC. (US) | 1993-11-24 | — | — | EP | disclosed |