SCHEMBL432297

SCHEMBL432297

O=C(Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2F)c(=O)n1)c1ccccc1

nearest known ligand 0.92

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 5/20 0.61
P2RY14 Q15391 2/20 0.61
NT5E P21589 1/20 0.61
ABL1 P00519 1/20 0.59
RIN1 Q13671 1/20 0.59
POLB P06746 1/20 0.58
LMNA P02545 1/20 0.50
THRB P10828 1/20 0.50
MTOR P42345 1/20 0.50
MDM2 Q00987 1/20 0.50
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
P2RY2 P41231 3/20 0.48
P2RY4 P51582 3/20 0.48
MAPT P10636 1/20 0.45
CDA P32320 1/20 0.45
ST6GAL1 P15907 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL881950 1.00 P2RY6 (0.61) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL432298 1.00 P2RY6 (0.61) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL432296 1.00 P2RY6 (0.61) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL22972654 0.94 P2RY6 (0.55) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL31160212 0.93 P2RY6 (0.61) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL16904894 0.93 P2RY6 (0.61) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL31160188 0.93 P2RY6 (0.61) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL18852530 0.92 P2RY6 (0.70) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL565905 0.92 P2RY6 (0.70) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL16805383 0.92 P2RY6 (0.70) P2RY6P2RY14NT5EABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 EP disclosed
WO-2026104647-A1 VACCINE ASTRAZENECA AB (SE) 2026-05-21 WO disclosed
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-10-09 US disclosed
WO-2025125630-A1 METHOD FOR BIOPROTAC DESIGN MEDIMMUNE LIMITED (GB) 2025-06-19 WO disclosed
US-12269841-B2 Production method for oligonucleotides AJINOMOTO CO., INC. (JP) 2025-04-08 US disclosed
EP-4522628-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF Adarx Pharmaceuticals, Inc. (US) 2025-03-19 EP disclosed
US-20250041400-A1 RSV VACCINE ASTRAZENECA PHARMACEUTICALS LP 2025-02-06 US disclosed
WO-2025017142-A1 RSV VACCINE ASTRAZENECA AB (SE) 2025-01-23 WO disclosed
WO-2023220737-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2023-11-16 WO disclosed
EP-2270024-B1 Antisense modulation of superoxide dismutase 1, soluble expression IONIS PHARMACEUTICALS INC (US) 2018-10-24 EP disclosed
US-5962672-A OLIGONUCLEOTIDES AGAINST NUCLEIC ACID WHICH CODES FOR SMALL GUANOSINE TRIPHOSPHATASE IMPORTANT IN REGULATION OF CYTOSKELETON DURING CELL CYCLE; FOR ANTICARCINOGENIC/ANTITUMOR AGENTS ISIS PHARMACEUTICALS INC. (US) 1999-10-05 US disclosed
US-5962671-A OLIGONUCLEOTIDE WHICH SUPPRESSES GENE EXPRESSION OF FACTOR ASSOCIATED WITH NEUTRAL SPHINGOMYELINASE ACTIVATION; FACTOR IS IS A MEDIATOR OF TUMOR NECROSIS FACTOR ACTIVATION OF THAT ENZYME THROUGH A SIGNAL TRANSDUCTION PATHWAY; GENE THERAPY ISIS PHARMACEUTICALS INC. (US) 1999-10-05 US disclosed
US-5962673-A ANTISENSE AGENT 8 TO 30 NUCLEOBASES IN LENGTH; FOR DIAGNOSIS AND TREATMENT OF ASTHMA, MYASTHENIA GRAVIS, GRAVES' DISEASE, ALLOGRAFT REJECTION, PSORIASIS AND OTHERS; ANTITUMOR/ ANTIPROLIFERATIVE/ANTIDIABETIC/ANTIARTHRITIC AGENTS ISIS PHARMACEUTICALS INC. (US) 1999-10-05 US disclosed
US-5959097-A OLIGONUCLEOTIDE OF 8 TO 30 NUCLEOTIDES WHICH SUPPRESSES EXPRESSION OF SIGNAL TRANSDUCTION KINASE; FOR TREATMENT OF INFECTIONS; ANTIINFLAMMATORY/ANTITUMOR AGENTS ISIS PHARMACEUTICALS, INC. (US) 1999-09-28 US disclosed
US-5958771-A OLIGONUCLEOTIDE FROM 8 TO 30 NUCLEOTIDES IN LENGTH; FOR DIAGNOSIS AND THERAPY; ANTITUMOR/ANTIINFLAMMATORY AGENTS ISIS PHARMACEUTICALS, INC. (US) 1999-09-28 US disclosed
US-5958772-A TARGETS TO NUCLEIC ACID MOLECULE ENCODING HUMAN CELLULAR INHIBITORS OF APOTOPSIS-1 ISIS PHARMACEUTICALS INC. (US) 1999-09-28 US disclosed
US-5958773-A ANTISENSE COMPOUND 8 TO 30 NUCLEOTIDES IN LENGTH TARGETED TO A NUCLEIC ACID ENCODING HUMAN AKT-1, OF THE SERINE/THREONINE KINASE FAMILY INVOLVED IN SIGNALLING PATHWAYS; INHIBITING EXPRESSION OF AKT-1 WITH THE ANTISENSE COMPOUND ISIS PHARMACEUTICALS INC. (US) 1999-09-28 US disclosed
US-5951455-A OLIGONUCLEOTIDES, TARGETED TO NUCLEIC ACIDS WITH MODULATION AND EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1999-09-14 US disclosed
US-5948680-A ANTISENSE OLIGONUCLEOTIDE TARGETED TO NUCLEIC ACIDS ENCODING ELK-1; ANTIPROLIFERATIVE AGENTS ISIS PHARMACEUTICALS INC. (US) 1999-09-07 US disclosed
US-5945290-A OLIGONUCLEOTIDES TARGETED AGAINST SPECIFIC NUCLEIC ACIDS; FOR ANTITUMOR/ANTICARCINOGENIC AGENTS; DIAGNOSIS AND THERAPY OF RELATED DISEASES ISIS PHARMACEUTICALS, INC. (US) 1999-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF POLRMT, TARDBP, NSUN2 P2RY6 2563/4885P2RY14 2588/4885NT5E 163/4885
US-20250041400-A1 RSV VACCINE LSS, SLFN12, FDPS P2RY6 4720/4885P2RY14 4373/4885NT5E 3529/4885
US-12269841-B2 Production method for oligonucleotides RNGTT, DCLRE1B, PHOSPHO1 P2RY6 2497/4885P2RY14 3336/4885NT5E 109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.