Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.73 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30758629 | 0.98 | MEN1 (0.80) | MEN1KMT2AKCNMA1EPHX1HDAC1 | |
| SCHEMBL3793263 | 0.88 | KCNMA1 (0.76) | MEN1KMT2AKCNMA1EPHX1KDM4E | |
| SCHEMBL9300675 | 0.87 | EPHX1 (0.74) | MEN1KMT2AKCNMA1EPHX1HDAC1 | |
| SCHEMBL8804658 | 0.86 | KDM4E (0.82) | MEN1KMT2AKCNMA1KDM4ENPSR1 | |
| SCHEMBL9362200 | 0.85 | HDAC1 (0.68) | MEN1KMT2AKCNMA1HDAC1HDAC8 | |
| SCHEMBL3790049 | 0.85 | MAPT (0.83) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL20612888 | 0.85 | HDAC1 (0.68) | MEN1KMT2AKCNMA1EPHX1HDAC1 | |
| SCHEMBL14476825 | 0.85 | KCNMA1 (1.00) | MEN1KMT2AKCNMA1HDAC1POLB | |
| SCHEMBL1520032 | 0.83 | KCNMA1 (0.75) | MEN1KMT2AKCNMA1HDAC1HDAC8 | |
| SCHEMBL31670343 | 0.83 | KCNMA1 (0.69) | MEN1KMT2AKCNMA1EPHX1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |