Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233411 | 0.88 | F2 (0.43) | F2PRSS1PRSS2PRSS3ELANE | |
| SCHEMBL7224920 | 0.80 | ALDH1A1 (0.42) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6850665 | 0.77 | F2 (0.55) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6027957 | 0.71 | F2 (0.48) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14423560 | 0.69 | F2 (0.38) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7363189 | 0.69 | F2 (0.43) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7341001 | 0.69 | F2 (0.56) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6358400 | 0.68 | F2 (0.43) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6028532 | 0.67 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7340775 | 0.67 | F2 (0.45) | F2PRSS1PRSS2PRSS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046207-A2 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-11 | — | — | WO | disclosed |