Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820117 | 0.89 | ALDH1A1 (0.48) | LMNAL3MBTL1ALDH1A1TP53PDE5A | |
| SCHEMBL8820113 | 0.87 | P2RX4 (0.44) | LMNAL3MBTL1ALDH1A1TP53PDE5A | |
| SCHEMBL8820115 | 0.86 | CYP2C19 (0.44) | ALDH1A1PDE5AMEN1KMT2AMAPT | |
| SCHEMBL1459895 | 0.84 | PDE5A (0.46) | LMNAL3MBTL1ALDH1A1PDE5ASMN1; SMN2 | |
| SCHEMBL2482539 | 0.83 | P2RX4 (0.48) | L3MBTL1ALDH1A1PDE5ASMN1; SMN2MEN1 | |
| SCHEMBL26647342 | 0.82 | PDE5A (0.41) | ALDH1A1PDE5AMEN1KMT2AMAPT | |
| SCHEMBL9045039 | 0.81 | NOTUM (0.61) | PDE5ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL12571561 | 0.80 | HTT (0.62) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11980498 | 0.80 | NOTUM (0.64) | LMNAALDH1A1PDE5ASMN1; SMN2MEN1 | |
| SCHEMBL6178827 | 0.80 | DPP4 (0.44) | LMNAPDE5ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997036895-A1 | PROCESS FOR THE PREPARATION OF TENIDAP | EGIS Gyógyszergyár Rt. (HU) | 1997-10-09 | — | — | WO | disclosed |