Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.55 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12451965 | 0.86 | PPARA (0.56) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL13956396 | 0.85 | PPARA (0.55) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL24021292 | 0.82 | PPARA (0.62) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL20222976 | 0.82 | PPARA (0.56) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL24021212 | 0.82 | FFAR4 (0.56) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL27809558 | 0.82 | FFAR4 (0.56) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL347209 | 0.82 | FFAR4 (0.61) | FFAR1FFAR4PLA2G4AALOX5OR51E2 | |
| SCHEMBL585819 | 0.81 | FFAR4 (0.60) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL15839483 | 0.81 | PPARA (0.56) | PPARAPPARDFFAR1FFAR4FFAR2 | |
| SCHEMBL8984877 | 0.81 | FFAR1 (0.57) | PPARAPPARDFFAR1FFAR4FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047295-A1 | SUBSTITUTED METHOXY BENZYLIDENE INDENYL-ACETIC AND PROPIONIC ACIDS FOR TREATING PATIENTS WITH PRECANCEROUS LESIONS | CELL PATHWAYS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |