Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220693 | 0.90 | NR1H2 (0.61) | NR1H2NR1H3 | |
| SCHEMBL31694045 | 0.87 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL14367891 | 0.87 | NR1H2 (0.75) | NR1H2NR1H3 | |
| SCHEMBL17220684 | 0.86 | NR1H2 (0.62) | NR1H2NR1H3 | |
| SCHEMBL16760212 | 0.86 | NR1H2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL17220643 | 0.86 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL17220656 | 0.84 | NR1H2 (0.67) | NR1H2NR1H3 | |
| SCHEMBL3001991 | 0.83 | NR1H2 (0.65) | NR1H2NR1H3 | |
| SCHEMBL23320505 | 0.82 | CYP19A1 (0.59) | NR1H2NR1H3 | |
| SCHEMBL27983070 | 0.81 | NR1H2 (0.48) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9169729-A | — | — | None | — | — | JP | disclosed |
| US-9527812-B2 | N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles | NORTHWESTERN UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527812-B2 | N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles | NORTHWESTERN UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527812-B2 | N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles | NORTHWESTERN UNIVERSITY (US) | 2016-12-27 | — | — | US | disclosed |
| US-20150315143-A1 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles | NORTHWESTERN UNIVERSITY | 2015-11-05 | — | — | US | disclosed |
| US-20150315143-A1 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles | NORTHWESTERN UNIVERSITY | 2015-11-05 | — | — | US | disclosed |
| US-20150315143-A1 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles | NORTHWESTERN UNIVERSITY | 2015-11-05 | — | — | US | disclosed |
| JP-H09169729-A | NONPEPTIDIC TYPE INTERLEUKIN 8 ANTAGONIST | GREEN CROSS CORP:THE | 1997-06-30 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315143-A1 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles | IDO2, IDO1, TPH2 | NR1H2 4475/4885NR1H3 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.