Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938455 | 0.84 | HTT (0.38) | HTTKMT2ATACR1TSHRSLC1A1 | |
| SCHEMBL13595500 | 0.82 | CA1 (0.41) | CA1CA2CA7CA9PPARA | |
| SCHEMBL21727813 | 0.78 | MAPT (0.36) | CA1KMT2ASLC1A1 | |
| SCHEMBL9465776 | 0.77 | TRPA1 (0.40) | CA1CA2CA7CA9PPARA | |
| SCHEMBL21727833 | 0.77 | TSHR (0.44) | CA1CA2CA7CA9KDM4E | |
| SCHEMBL21727779 | 0.76 | MAPT (0.34) | CA1CA2CA7CA9HTT | |
| SCHEMBL13595460 | 0.76 | CA1 (0.38) | CA1CA2CA7CA9PPARA | |
| SCHEMBL13595496 | 0.76 | CA1 (0.38) | CA1CA2CA7CA9PPARA | |
| SCHEMBL9788246 | 0.75 | CA1 (0.38) | CA1CA2CA7CA9PPARA | |
| SCHEMBL4570494 | 0.75 | CA1 (0.42) | CA1CA2CA7CA9PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032879-A1 | 7-ALKYL-PYRROLO[2,3-d]PYRIMIDINES | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |