Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.65 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.65 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570922 | 1.00 | S1PR2 (0.65) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9407912 | 0.98 | S1PR2 (0.67) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL4388150 | 0.96 | S1PR2 (0.64) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL10716895 | 0.93 | S1PR2 (0.56) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL14823591 | 0.91 | S1PR2 (0.60) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL8818989 | 0.91 | S1PR2 (0.65) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3118701 | 0.91 | S1PR2 (0.65) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL3118704 | 0.91 | S1PR2 (0.65) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL8818981 | 0.91 | S1PR2 (0.65) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL21984539 | 0.89 | S1PR2 (0.61) | S1PR2S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9295937-A | — | — | None | — | — | JP | disclosed |
| JP-H09295937-A | SIGMA RECEPTOR BONDING INHIBITOR | SUMITOMO PHARMACEUT CO LTD | 1997-11-18 | — | — | JP | disclosed |