Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ABL2 | P42684 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820974 | 0.87 | GPR119 (0.49) | GPR119FAAHCPT1A | |
| SCHEMBL14924229 | 0.84 | GPR119 (0.61) | GPR119FAAHPOLBHDAC4KDM4E | |
| SCHEMBL8820917 | 0.81 | GPR119 (0.54) | GPR119FAAHHDAC4 | |
| SCHEMBL390317 | 0.79 | GPR119 (0.74) | GPR119FAAHHDAC4KDM4EPKM | |
| SCHEMBL15785127 | 0.79 | GPR119 (0.62) | GPR119FAAHPOLBHDAC4KDM4E | |
| SCHEMBL3188476 | 0.79 | GPR119 (0.46) | GPR119HDAC4 | |
| SCHEMBL8820926 | 0.79 | GPR119 (0.51) | GPR119ABL1EGFRSRCABL2 | |
| SCHEMBL30812262 | 0.79 | GPR119 (0.51) | GPR119FAAHTGFBR1KDM4EPKM | |
| SCHEMBL4414146 | 0.77 | GPR119 (0.58) | GPR119HDAC4KDM4EPKM | |
| SCHEMBL4417372 | 0.76 | GPR119 (0.57) | GPR119HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044333-A1 | 1,2,4-OXADIAZOLES AS ADHESION-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1997-11-27 | — | — | WO | disclosed |