Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | KIT | P10721 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | RECQL | P46063 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | TLR3 | O15455 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.63 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.59 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837747 | 0.90 | KIT (0.64) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL10507648 | 0.86 | KIT (0.73) | KMT2AKITMAPTRECQLMEN1 | |
| Hydrochloric Acid SCHEMBL11068466 | 0.85 | KIT (0.71) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL11832110 | 0.83 | KIT (0.69) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL11831087 | 0.83 | KIT (0.69) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL11826831 | 0.83 | KIT (0.64) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL612787 | 0.82 | LIMK1 (0.67) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL11218842 | 0.82 | KIT (0.56) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL8821017 | 0.82 | KIT (0.69) | KMT2AKITMAPTRECQLMEN1 | |
| SCHEMBL9414046 | 0.81 | KIT (0.65) | KMT2AKITMAPTRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046559-A1 | PROCESS FOR PREPARING 9-HYDROXYELLIPTICINE | TANABE SEIYAKU CO., LTD. (JP) | 1997-12-11 | — | — | WO | disclosed |
| US-3933827-A | CYTOSTATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-01-20 | — | — | US | disclosed |