Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.67 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KIT | P10721 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TLR3 | O15455 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821071 | 0.82 | KMT2A (0.66) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL613967 | 0.81 | KDM4E (0.63) | KMT2AKDM4EMAPTKITMEN1 | |
| SCHEMBL612219 | 0.80 | LIMK1 (1.00) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL11837747 | 0.77 | KIT (0.64) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL11066204 | 0.75 | LIMK1 (0.62) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL12071304 | 0.73 | MAOA (0.63) | KMT2AKDM4EMAPTMEN1NPSR1 | |
| SCHEMBL10022324 | 0.71 | LIMK1 (0.59) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL10571821 | 0.71 | LIMK1 (0.68) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL10563584 | 0.70 | LIMK1 (0.53) | LIMK1LIMK2KMT2AKDM4EMAPT | |
| SCHEMBL9736132 | 0.69 | KDM4E (0.65) | KMT2AKDM4EMAPTKITMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604048-B2 | Pyridocarbazole type compounds and applications thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-10 | — | — | US | disclosed |
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041017-A1 | PYRIDOCARBAZOLE TYPE COMPOUNDS AND APPLICATIONS THEREOF | NLN, OPA1, PYCR1 | LIMK1 2270/4885LIMK2 2037/4885KMT2A 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.