Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | TLR3 | O15455 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831087 | 0.91 | KIT (0.69) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL10507648 | 0.85 | KIT (0.73) | KITRECQLKDM4EMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11068466 | 0.84 | KIT (0.71) | KITRECQLKDM4EMAPTRAB9A | |
| Lactic Acid SCHEMBL8427098 | 0.83 | KIT (0.80) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL8821017 | 0.83 | KIT (0.69) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL11832110 | 0.82 | KIT (0.69) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL1005968 | 0.81 | KIT (1.00) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL8821071 | 0.81 | KMT2A (0.66) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL9414046 | 0.80 | KIT (0.65) | KITRECQLKDM4EMAPTRAB9A | |
| SCHEMBL11837747 | 0.79 | KIT (0.64) | KITRECQLKDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046559-A1 | PROCESS FOR PREPARING 9-HYDROXYELLIPTICINE | TANABE SEIYAKU CO., LTD. (JP) | 1997-12-11 | — | — | WO | disclosed |
| US-5605904-A | ANTITUMOR AGENTS; ANTICARCINOGENIC AGENTS; FEWER SIDE EFFECTS | TANABE SEIYAKU CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5565569-A | ANTITUMOR AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0608876-A1 | Ellipticine derivatives with antitumour activity | TANABE SEIYAKU CO., LTD. (JP) | 1994-08-03 | — | — | EP | disclosed |