Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384061 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL16300870 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL780151 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL384063 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL8322180 | 0.85 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL6101745 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL882273 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL10249272 | 0.84 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL22509003 | 0.82 | SLC6A4 (0.49) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL6102641 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040126-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-29 | — | — | WO | disclosed |