Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056844 | 0.89 | MTNR1A (0.44) | MTNR1AMTNR1BSMN1; SMN2TRPV1 | |
| SCHEMBL7058321 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7055344 | 0.81 | MTNR1A (0.54) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7054074 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8822773 | 0.77 | MTNR1A (0.35) | MTNR1AMTNR1BSMN1; SMN2TRPV1 | |
| SCHEMBL7054305 | 0.76 | MTNR1A (0.47) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL8822728 | 0.76 | MTNR1A (0.57) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7057879 | 0.76 | MTNR1A (0.65) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7051696 | 0.76 | MTNR1A (0.64) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7058314 | 0.76 | MTNR1A (0.35) | MTNR1AMTNR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000069-A1 | MELATONIN AGONISTS FOR TREATING BENIGN PROSTATIC HYPERPLASIA | ELI LILLY AND COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |