Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055969 | 0.86 | MTNR1A (0.79) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL7052855 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL9671286 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL9671722 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL7055939 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL7051639 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL7055786 | 0.74 | MTNR1A (0.75) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL8437093 | 0.74 | MTNR1A (0.78) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL7055084 | 0.73 | MTNR1A (0.54) | MTNR1AMTNR1BTRPV1HTR2BHTR2A | |
| SCHEMBL10566437 | 0.73 | MTNR1A (0.77) | MTNR1AMTNR1BTRPV1HTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000069-A1 | MELATONIN AGONISTS FOR TREATING BENIGN PROSTATIC HYPERPLASIA | ELI LILLY AND COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |