Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | SLCO2A1 | Q92959 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823014 | 1.00 | PTGFR (0.47) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL8823023 | 0.88 | PTGFR (0.48) | PTGFRALDH1A1PTGER3TBXA2RPTGER1 | |
| SCHEMBL8823026 | 0.88 | PTGFR (0.48) | PTGFRALDH1A1PTGER3TBXA2RPTGER1 | |
| SCHEMBL8822912 | 0.87 | SLCO2A1 (0.41) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL8822915 | 0.87 | SLCO2A1 (0.41) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL9849477 | 0.86 | MEN1 (0.37) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL8822848 | 0.86 | MEN1 (0.37) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL8822936 | 0.83 | PTGER2 (0.42) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL8822934 | 0.83 | PTGER2 (0.42) | PTGFRALDH1A1PTGER3TBXA2RLMNA | |
| SCHEMBL8822969 | 0.79 | TRPA1 (0.48) | PTGFRALDH1A1PTGER3TBXA2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454429-B1 | Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases | R TECH UENO LTD (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0444844-B1 | New 15-dehydroxy-16-oxoprostaglandins | R TECH UENO LTD (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5221799-A | New 15-dehydroxy-16-oxoprostaglandins | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0454429-A2 | Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1991-10-30 | — | — | EP | disclosed |
| EP-0444844-A2 | New 15-dehydroxy-16-oxoprostaglandins | R-TECH UENO LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |