Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 10/20 | 0.42 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.37 |
| ▸ | RXRB | P28702 | 4/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936223 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGPPARARXRARXRB | |
| SCHEMBL8935642 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARGPPARARXRARXRB | |
| SCHEMBL8935640 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARGPPARARXRARXRB | |
| SCHEMBL8527020 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2PPARGPPARAPTGESALOX5 | |
| SCHEMBL11742983 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL2280554 | 0.77 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARGPPARAPTGESALOX5 | |
| SCHEMBL8823318 | 0.77 | TDP1 (0.51) | SMN1; SMN2PPARGPPARARXRARXRB | |
| SCHEMBL3942614 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL11359371 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2PPARGPPARAPTGESALOX5 | |
| SCHEMBL8935975 | 0.75 | PPARG (0.71) | SMN1; SMN2PPARGPPARAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492350-B1 | Process for the production of (S)-vinyl and (S) allenyl gaba | MERRELL PHARMA INC (US) | 1997-10-15 | — | — | EP | disclosed |