SCHEMBL8823482

SCHEMBL8823482

CCCCCCC(=O)N[C@@H](C(=O)O)[C@H](C)O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
MAPK1 P28482 1/20 0.62
NOD1 Q9Y239 3/20 0.55
PLA2G2A P14555 1/20 0.55
PLA2G5 P39877 1/20 0.55
ALDH1A1 P00352 1/20 0.52
ASAH1 Q13510 1/20 0.52
ACER2 Q5QJU3 1/20 0.52
DNM1 Q05193 1/20 0.51
PLA2G2C Q5R387 1/20 0.51
PLA2G10 O15496 2/20 0.51
ASAH2 Q9NR71 1/20 0.50
HSP90AA1 P07900 1/20 0.48
SLC6A5 Q9Y345 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667184 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL17204243 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL543568 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL17203963 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL7268170 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL25196976 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL11047279 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL7269318 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL11047281 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1
SCHEMBL338364 1.00 FAAH (0.62) FAAHMEN1KMT2AMAPK1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1094943-C Urethanes and ureas that induce cytokine production AMERICAN CYANAMID CO (US) 2002-11-27 CN disclosed
US-5658945-A ANTICANCER AGENT; AIDS THERAPY; CONTROLLING INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-08-19 US disclosed
US-5633280-A ACCELERATED RECOVERY FROM CHEMOTHERAPY, RADIATION TREATMENT, BONE MARROW TRANSPLANTATION, INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-05-27 US disclosed
US-5616612-A THERAPY FOR CANCER, AIDS, ANEMIA, INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-04-01 US disclosed
US-5602275-A MAY BE USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO- OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION OR INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-02-11 US disclosed
EP-0652228-B1 Urethanes and ureas that induce cytokine production AMERICAN CYANAMID CO (US) 1996-10-23 EP disclosed
US-5545662-A USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION, OR INFECTIONS AMERICAN CYANAMID COMPANY (US) 1996-08-13 US disclosed
EP-0652228-A1 Urethanes and ureas that induce cytokine production AMERICAN CYANAMID COMPANY (US) 1995-05-10 EP disclosed
CN-1100413-A Urethanes and ureas that induce cytokine production AMERICAN CYANAMID CO (US) 1995-03-22 CN disclosed
US-5312831-A Immunology, anticarcinogenic agents and AIDS treatment AMERICAN CYANAMID COMPANY (US) 1994-05-17 US disclosed