SCHEMBL8823490

SCHEMBL8823490

CCCCCCC(=O)N[C@H](CO)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 5/20 0.71
FAAH O00519 5/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
MAPK1 P28482 1/20 0.59
SLC6A5 Q9Y345 1/20 0.56
DNM1 Q05193 1/20 0.53
PLA2G2C Q5R387 1/20 0.53
THRB P10828 1/20 0.52
DEGS1 O15121 1/20 0.52
ASAH1 Q13510 1/20 0.52
CETP P11597 1/20 0.52
EPHX2 P34913 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770695 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL193476 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL15650882 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL25192010 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL17203900 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL25192009 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL17203784 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL5333001 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL19475767 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1
SCHEMBL19744696 1.00 NOD1 (0.71) NOD1FAAHMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1094943-C Urethanes and ureas that induce cytokine production AMERICAN CYANAMID CO (US) 2002-11-27 CN disclosed
US-5658945-A ANTICANCER AGENT; AIDS THERAPY; CONTROLLING INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-08-19 US disclosed
US-5633280-A ACCELERATED RECOVERY FROM CHEMOTHERAPY, RADIATION TREATMENT, BONE MARROW TRANSPLANTATION, INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-05-27 US disclosed
US-5616612-A THERAPY FOR CANCER, AIDS, ANEMIA, INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-04-01 US disclosed
US-5602275-A MAY BE USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO- OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION OR INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-02-11 US disclosed
EP-0652228-B1 Urethanes and ureas that induce cytokine production AMERICAN CYANAMID CO (US) 1996-10-23 EP disclosed
US-5545662-A USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION, OR INFECTIONS AMERICAN CYANAMID COMPANY (US) 1996-08-13 US disclosed
EP-0652228-A1 Urethanes and ureas that induce cytokine production AMERICAN CYANAMID COMPANY (US) 1995-05-10 EP disclosed
CN-1100413-A Urethanes and ureas that induce cytokine production AMERICAN CYANAMID CO (US) 1995-03-22 CN disclosed
US-5312831-A Immunology, anticarcinogenic agents and AIDS treatment AMERICAN CYANAMID COMPANY (US) 1994-05-17 US disclosed
US-3950277-A LIPASE ENZYME AND ACTIVATORS, ALKYLNAPHTHALENE SULFONATE THE PROCTER & GAMBLE COMPANY (US) 1976-04-13 US disclosed