SCHEMBL88235

SCHEMBL88235

C=CCSCCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28348859 0.83 ALOX5 (0.43)
SCHEMBL28348510 0.81 ALOX5 (0.42)
SCHEMBL17953254 0.80
SCHEMBL27887063 0.80
SCHEMBL2423219 0.76
SCHEMBL10824237 0.76 ALOX5 (0.71)
SCHEMBL2260309 0.75
SCHEMBL11031747 0.74
SCHEMBL9770408 0.74 TDP1 (0.53)
SCHEMBL7633989 0.74 ALOX5 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001215-B Catalytic oxidation of 3-butene-1, 2-diol (BDO) 安迪苏法国联合股份有限公司 2021-09-07 CN disclosed
US-10442760-B2 Catalytic oxidation of but-3-ene-1,2-diol ADISSEO FRANCE S.A.S. (FR) 2019-10-15 US disclosed
US-20170342029-A1 CATALYTIC OXIDATION OF BUT-3-ENE-1,2-DIOL ADISSEO FRANCE S.A.S. (FR) 2017-11-30 US disclosed
EP-2646416-B9 IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES DOW AGROSCIENCES LLC (US) 2016-12-21 EP disclosed
EP-2646416-B1 IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES DOW AGROSCIENCES LLC (US) 2016-09-07 EP disclosed
CN-102105447-B Sulfoximinamide compounds for combating animal pests BASF SE 2014-06-04 CN disclosed
US-8742125-B2 Process for the preparation of 2-trifluoromethyl-5-(1-substituted)alkylpyridines DOW AGROSCIENCES, LLC. (US) 2014-06-03 US disclosed
EP-2646416-A2 IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES Dow AgroSciences LLC (US) 2013-10-09 EP disclosed
CN-102137845-B Improved process for preparing 2-trifluoromethyl-5- (1-substituted) alkylpyridines DOW AGROSCIENCES LLC 2013-09-04 CN disclosed
CN-101107223-B Preparation of 3-(alkylthio) propanal EVONIK DEGUSSA GMBH 2013-03-27 CN disclosed
US-4405617-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-09-20 US disclosed
US-4385176-A RING EXPANSION USING A LEWIS ACID FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-05-24 US disclosed
US-4308380-A 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-29 US disclosed
EP-0033965-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-08-19 EP disclosed
US-4203897-A Penam derivatives FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-05-20 US disclosed
US-4113940-A ANTIMICROBIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1978-09-12 US disclosed
US-4091210-A Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-05-23 US disclosed
US-4084049-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-04-11 US disclosed
US-3984397-A CYCLIZATION FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-10-05 US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US disclosed