Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823845 | 1.00 | DRD2 (0.73) | DRD2 | |
| SCHEMBL9441732 | 0.89 | DRD2 (0.60) | DRD2 | |
| SCHEMBL8823777 | 0.86 | DRD2 (0.69) | DRD2 | |
| SCHEMBL8823771 | 0.86 | DRD2 (0.68) | DRD2 | |
| SCHEMBL8823779 | 0.86 | DRD2 (0.68) | DRD2 | |
| SCHEMBL8823677 | 0.85 | DRD2 (0.64) | DRD2 | |
| Hydrochloric Acid SCHEMBL9619871 | 0.84 | DRD2 (0.62) | DRD2 | |
| Hydrochloric Acid SCHEMBL9786965 | 0.84 | DRD2 (0.62) | DRD2 | |
| SCHEMBL8823740 | 0.84 | DRD2 (0.69) | DRD2 | |
| SCHEMBL8823612 | 0.84 | DRD2 (0.65) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656657-A | Chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-08-12 | — | — | US | disclosed |
| US-5656658-A | Method for the treatment of anxiety | ASTRA AKTIEBOLAG (SE) | 1997-08-12 | — | — | US | disclosed |
| US-5650524-A | Process for preparing (R)-3-amino-5-methoxychroman | ASTRA AKTIEBOLAG (SE) | 1997-07-22 | — | — | US | disclosed |
| US-5646309-A | Intermediates in the synthesis of chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-07-08 | — | — | US | disclosed |
| US-5641807-A | Method for the treatment of depression | ASTRA AKTIEBOLAG (SE) | 1997-06-24 | — | — | US | disclosed |
| US-5639772-A | Chroman derivatives | ASTRA AKTIEBOLAG (SE) | 1997-06-17 | — | — | US | disclosed |
| US-5639784-A | ADMINISTERING 3-AMINO-5-CARBAMOYL-CHROMENES AND DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1997-06-17 | — | — | US | disclosed |
| EP-0607274-B1 | 3-(N-ISOPROPYL-N-n-PROPYLAMINO)-5-(N-ISOPROPYL)CARBAMOYLCHROMAN | ASTRA AB (SE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0703229-A2 | Process for the preparation of (R)-3-amino-5-methoxychroman | Astra Aktiebolag (SE) | 1996-03-27 | — | — | EP | disclosed |
| US-5500425-A | Chroman derivatives and a method of treating 5-HT mediated disorders | AKTIEBOLAGET ASTRA (SE) | 1996-03-19 | — | — | US | disclosed |
| US-5420151-A | Chroman derivatives | AKTIEBOLAGET ASTRA (SE) | 1995-05-30 | — | — | US | disclosed |
| EP-0607274-A1 | 3-(N-ISOPROPYL-N-n-PROPYLAMINO)-5-(N-ISOPROPYL)CARBAMOYLCHROMAN. | ASTRA AB (SE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0538222-A1 | 3-(N-Isopropyl-N-n-propylamino)-5-(N-isopropyl)carbamoylchroman as a selective 5-hydroxytryptamine receptor stimulant | Astra Aktiebolag (SE) | 1993-04-21 | — | — | EP | disclosed |
| WO-1993007135-A1 | 3-(N-ISOPROPYL-N-N-PROPYLAMINO)-5-(N-ISOPROPYL)CARBAMOYLCHROMAN | AKTIEBOLAGET ASTRA (SE) | 1993-04-15 | — | — | WO | disclosed |