Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824085 | 1.00 | PARP1 (0.47) | PARP1KCNH2GRM2HTR3ASCN9A | |
| SCHEMBL8824093 | 0.86 | PARP1 (0.55) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL9243355 | 0.86 | PARP1 (0.55) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8823991 | 0.85 | PARP1 (0.58) | PARP1KCNH2GRM2HTR3ALMNA | |
| SCHEMBL8824089 | 0.85 | PARP1 (0.45) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8823994 | 0.85 | PARP1 (0.58) | PARP1KCNH2GRM2HTR3ALMNA | |
| SCHEMBL8824092 | 0.85 | PARP1 (0.45) | PARP1KCNH2GRM2HTR3AKDM4E | |
| SCHEMBL8824037 | 0.81 | PARP1 (0.42) | PARP1KCNH2GRM2HTR3ALMNA | |
| SCHEMBL8824032 | 0.81 | PARP1 (0.42) | PARP1KCNH2GRM2HTR3ALMNA | |
| SCHEMBL9243297 | 0.71 | PARP1 (0.53) | PARP1KCNH2GRM2HTR3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643920-A | PYRROLO(3,2,1-IJ)QUINOLINES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0638570-A1 | TRICYCLIC COMPOUND HAVING ANTIALLERGIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |